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GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer

Inflammation is frequently associated with initiation, progression, and metastasis of colorectal cancer (CRC). Here, we unveil a CRC-specific metastatic programme that is triggered via the transcriptional repressor, GFI1. Using data from a large cohort of clinical samples including inflammatory bowe...

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Detalles Bibliográficos
Autores principales: Xing, Wenjing, Xiao, Yun, Lu, Xinliang, Zhu, Hongyan, He, Xiangchuan, Huang, Wei, Lopez, Elsa S, Wong, Jerry, Ju, Huanyu, Tian, Linlu, Zhang, Fengmin, Xu, Hongwei, Wang, Sheng Dian, Li, Xia, Karin, Michael, Ren, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423119/
https://www.ncbi.nlm.nih.gov/pubmed/28387757
http://dx.doi.org/10.1038/cdd.2017.50