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Genetically Encoded 2-Aryl-5-carboxytetrazoles for Site-Selective Protein Photo-Cross-Linking

[Image: see text] The genetically encoded photo-cross-linkers promise to offer a temporally controlled tool to map transient and dynamic protein–protein interaction complexes in living cells. Here we report the synthesis of a panel of 2-aryl-5-carboxytetrazole-lysine analogs (ACTKs) and their site-s...

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Detalles Bibliográficos
Autores principales: Tian, Yulin, Jacinto, Marco Paolo, Zeng, Yu, Yu, Zhipeng, Qu, Jun, Liu, Wenshe R., Lin, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423124/
https://www.ncbi.nlm.nih.gov/pubmed/28422494
http://dx.doi.org/10.1021/jacs.7b02615