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Monitoring vascular normalization induced by antiangiogenic treatment with 18F‐fluoromisonidazole‐PET

Background: Rationalization of antiangiogenics requires biomarkers. Vascular re‐normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular normalization with 18F‐misonidazole ([18F]‐FMISO,...

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Detalles Bibliográficos
Autores principales:	Hernández-Agudo, Elena, Mondejar, Tamara, Soto-Montenegro, Maria Luisa, Megías, Diego, Mouron, Silvana, Sanchez, Jesus, Hidalgo, Manuel, Lopez-Casas, Pedro Pablo, Mulero, Francisca, Desco, Manuel, Quintela-Fandino, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423153/ https://www.ncbi.nlm.nih.gov/pubmed/26778791 http://dx.doi.org/10.1016/j.molonc.2015.12.011

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