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Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium

Redox homeostasis regulates key cellular signaling pathways in both physiology and pathology. The cell's antioxidant response provides a defense against oxidative stress and establishes a redox tone permissive for cell signaling. The molecular regulation of the well-known Keap1/Nrf2 system acts...

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Detalles Bibliográficos
Autores principales:	Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Tamowski, Susan, Darley-Usmar, Victor, Rajasekaran, Namakkal S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423345/ https://www.ncbi.nlm.nih.gov/pubmed/28482326 http://dx.doi.org/10.1016/j.redox.2017.04.038

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