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Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome

OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis...

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Autores principales: Abaci, Okay, Kocas, Cuneyt, Oktay, Veysel, Arslan, Sukru, Turkmen, Yusuf, Bostan, Cem, Coskun, Ugur, Yildiz, Ahmet, Ersanli, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423424/
https://www.ncbi.nlm.nih.gov/pubmed/28262908
http://dx.doi.org/10.5830/CVJA-2016-041
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author Abaci, Okay
Kocas, Cuneyt
Oktay, Veysel
Arslan, Sukru
Turkmen, Yusuf
Bostan, Cem
Coskun, Ugur
Yildiz, Ahmet
Ersanli, Murat
author_facet Abaci, Okay
Kocas, Cuneyt
Oktay, Veysel
Arslan, Sukru
Turkmen, Yusuf
Bostan, Cem
Coskun, Ugur
Yildiz, Ahmet
Ersanli, Murat
author_sort Abaci, Okay
collection PubMed
description OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis of NSTEMI were enrolled in our study. They were divided into tertiles according to the GS: low GS <19; mid GS > 19 and ≤ 96; and high GS > 96. RESULTS: The low-, mid- and high-GS groups included 24, 38 and 28 patients, respectively. Clinical features such as gender distribution; body mass index (BMI); prevalence of diabetes mellitus, hypertension and hyperlipidaemia; and smoking status were similar in the three groups. MPI and isovolumic relaxation time were significantly higher in the high-GS group than in the low- and mid-GS groups (p < 0.001 and p = 0.005, respectively). Furthermore, the high-GS group had a significantly lower ejection fraction and ejection time (p = 0.01 and p < 0.001, respectively). MPI was positively correlated with the GS (r = 0.47, p < 0.001), and multivariate regression analysis showed that MPI was an independent predictor of the GS (β = 0.358, p < 0.001). CONCLUSIONS: Patients with NSTEMI who fall within the high-risk group may be identified by means of a simple MPI measurement.
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spelling pubmed-54234242017-05-24 Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome Abaci, Okay Kocas, Cuneyt Oktay, Veysel Arslan, Sukru Turkmen, Yusuf Bostan, Cem Coskun, Ugur Yildiz, Ahmet Ersanli, Murat Cardiovasc J Afr Cardiovascular Topics OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis of NSTEMI were enrolled in our study. They were divided into tertiles according to the GS: low GS <19; mid GS > 19 and ≤ 96; and high GS > 96. RESULTS: The low-, mid- and high-GS groups included 24, 38 and 28 patients, respectively. Clinical features such as gender distribution; body mass index (BMI); prevalence of diabetes mellitus, hypertension and hyperlipidaemia; and smoking status were similar in the three groups. MPI and isovolumic relaxation time were significantly higher in the high-GS group than in the low- and mid-GS groups (p < 0.001 and p = 0.005, respectively). Furthermore, the high-GS group had a significantly lower ejection fraction and ejection time (p = 0.01 and p < 0.001, respectively). MPI was positively correlated with the GS (r = 0.47, p < 0.001), and multivariate regression analysis showed that MPI was an independent predictor of the GS (β = 0.358, p < 0.001). CONCLUSIONS: Patients with NSTEMI who fall within the high-risk group may be identified by means of a simple MPI measurement. Clinics Cardive Publishing 2017 /pmc/articles/PMC5423424/ /pubmed/28262908 http://dx.doi.org/10.5830/CVJA-2016-041 Text en Copyright © 2015 Clinics Cardive Publishing http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Topics
Abaci, Okay
Kocas, Cuneyt
Oktay, Veysel
Arslan, Sukru
Turkmen, Yusuf
Bostan, Cem
Coskun, Ugur
Yildiz, Ahmet
Ersanli, Murat
Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title_full Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title_fullStr Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title_full_unstemmed Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title_short Relationship between myocardial performance index and severity of coronary artery disease in patients with non-ST -segment elevation acute coronary syndrome
title_sort relationship between myocardial performance index and severity of coronary artery disease in patients with non-st -segment elevation acute coronary syndrome
topic Cardiovascular Topics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423424/
https://www.ncbi.nlm.nih.gov/pubmed/28262908
http://dx.doi.org/10.5830/CVJA-2016-041
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