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VCF-kit: assorted utilities for the variant call format
SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423453/ https://www.ncbi.nlm.nih.gov/pubmed/28093408 http://dx.doi.org/10.1093/bioinformatics/btx011 |
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author | Cook, Daniel E Andersen, Erik C |
author_facet | Cook, Daniel E Andersen, Erik C |
author_sort | Cook, Daniel E |
collection | PubMed |
description | SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet. To streamline these types of analyses, we created novel tools that analyze or annotate VCF files and organized these tools into a command-line based utility named VCF-kit. VCF-kit adds essential utilities to process and analyze VCF files, including primer generation for variant validation, dendrogram production, genotype imputation from sequence data in linkage studies, and additional tools. AVAILABILITY AND IMPLEMENTATION: https://github.com/AndersenLab/VCF-kit |
format | Online Article Text |
id | pubmed-5423453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-54234532017-05-11 VCF-kit: assorted utilities for the variant call format Cook, Daniel E Andersen, Erik C Bioinformatics Applications Notes SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet. To streamline these types of analyses, we created novel tools that analyze or annotate VCF files and organized these tools into a command-line based utility named VCF-kit. VCF-kit adds essential utilities to process and analyze VCF files, including primer generation for variant validation, dendrogram production, genotype imputation from sequence data in linkage studies, and additional tools. AVAILABILITY AND IMPLEMENTATION: https://github.com/AndersenLab/VCF-kit Oxford University Press 2017-05-15 2017-01-16 /pmc/articles/PMC5423453/ /pubmed/28093408 http://dx.doi.org/10.1093/bioinformatics/btx011 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Cook, Daniel E Andersen, Erik C VCF-kit: assorted utilities for the variant call format |
title | VCF-kit: assorted utilities for the variant call format |
title_full | VCF-kit: assorted utilities for the variant call format |
title_fullStr | VCF-kit: assorted utilities for the variant call format |
title_full_unstemmed | VCF-kit: assorted utilities for the variant call format |
title_short | VCF-kit: assorted utilities for the variant call format |
title_sort | vcf-kit: assorted utilities for the variant call format |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423453/ https://www.ncbi.nlm.nih.gov/pubmed/28093408 http://dx.doi.org/10.1093/bioinformatics/btx011 |
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