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VCF-kit: assorted utilities for the variant call format

SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet....

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Detalles Bibliográficos
Autores principales: Cook, Daniel E, Andersen, Erik C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423453/
https://www.ncbi.nlm.nih.gov/pubmed/28093408
http://dx.doi.org/10.1093/bioinformatics/btx011
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author Cook, Daniel E
Andersen, Erik C
author_facet Cook, Daniel E
Andersen, Erik C
author_sort Cook, Daniel E
collection PubMed
description SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet. To streamline these types of analyses, we created novel tools that analyze or annotate VCF files and organized these tools into a command-line based utility named VCF-kit. VCF-kit adds essential utilities to process and analyze VCF files, including primer generation for variant validation, dendrogram production, genotype imputation from sequence data in linkage studies, and additional tools. AVAILABILITY AND IMPLEMENTATION: https://github.com/AndersenLab/VCF-kit
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spelling pubmed-54234532017-05-11 VCF-kit: assorted utilities for the variant call format Cook, Daniel E Andersen, Erik C Bioinformatics Applications Notes SUMMARY: The variant call format (VCF) is a popular standard for storing genetic variation data. As a result, a large collection of tools has been developed that perform diverse analyses using VCF files. However, some tasks common to statistical and population geneticists have not been created yet. To streamline these types of analyses, we created novel tools that analyze or annotate VCF files and organized these tools into a command-line based utility named VCF-kit. VCF-kit adds essential utilities to process and analyze VCF files, including primer generation for variant validation, dendrogram production, genotype imputation from sequence data in linkage studies, and additional tools. AVAILABILITY AND IMPLEMENTATION: https://github.com/AndersenLab/VCF-kit Oxford University Press 2017-05-15 2017-01-16 /pmc/articles/PMC5423453/ /pubmed/28093408 http://dx.doi.org/10.1093/bioinformatics/btx011 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Cook, Daniel E
Andersen, Erik C
VCF-kit: assorted utilities for the variant call format
title VCF-kit: assorted utilities for the variant call format
title_full VCF-kit: assorted utilities for the variant call format
title_fullStr VCF-kit: assorted utilities for the variant call format
title_full_unstemmed VCF-kit: assorted utilities for the variant call format
title_short VCF-kit: assorted utilities for the variant call format
title_sort vcf-kit: assorted utilities for the variant call format
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423453/
https://www.ncbi.nlm.nih.gov/pubmed/28093408
http://dx.doi.org/10.1093/bioinformatics/btx011
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