Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference

Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the a...

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Detalles Bibliográficos
Autores principales: Hao, Nan, Palmer, Adam C., Dodd, Ian B., Shearwin, Keith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423467/
https://www.ncbi.nlm.nih.gov/pubmed/28129043
http://dx.doi.org/10.1080/21541264.2017.1285851
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author Hao, Nan
Palmer, Adam C.
Dodd, Ian B.
Shearwin, Keith E.
author_facet Hao, Nan
Palmer, Adam C.
Dodd, Ian B.
Shearwin, Keith E.
author_sort Hao, Nan
collection PubMed
description Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the ability of a transcription factor to relieve or induce TI.
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spelling pubmed-54234672017-05-17 Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference Hao, Nan Palmer, Adam C. Dodd, Ian B. Shearwin, Keith E. Transcription Point-of-View Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the ability of a transcription factor to relieve or induce TI. Taylor & Francis 2017-01-27 /pmc/articles/PMC5423467/ /pubmed/28129043 http://dx.doi.org/10.1080/21541264.2017.1285851 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Point-of-View
Hao, Nan
Palmer, Adam C.
Dodd, Ian B.
Shearwin, Keith E.
Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title_full Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title_fullStr Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title_full_unstemmed Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title_short Directing traffic on DNA—How transcription factors relieve or induce transcriptional interference
title_sort directing traffic on dna—how transcription factors relieve or induce transcriptional interference
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423467/
https://www.ncbi.nlm.nih.gov/pubmed/28129043
http://dx.doi.org/10.1080/21541264.2017.1285851
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