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Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy

Adenoviruses (Ads) infect a broad range of tissue types, and derived vectors have been extensively used for gene therapy. Helper-dependent Ad vectors (HDAds), devoid of viral coding sequences, allow for insertion of large or multiple transgenes in a single vector and have been preclinically used for...

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Detalles Bibliográficos
Autores principales: Farzad, Lisa M., Suzuki, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423480/
https://www.ncbi.nlm.nih.gov/pubmed/28548063
http://dx.doi.org/10.3390/biomedicines2010110