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Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy
Adenoviruses (Ads) infect a broad range of tissue types, and derived vectors have been extensively used for gene therapy. Helper-dependent Ad vectors (HDAds), devoid of viral coding sequences, allow for insertion of large or multiple transgenes in a single vector and have been preclinically used for...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423480/ https://www.ncbi.nlm.nih.gov/pubmed/28548063 http://dx.doi.org/10.3390/biomedicines2010110 |