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Design and Potential of Non-Integrating Lentiviral Vectors

Lentiviral vectors have demonstrated promising results in clinical trials that target cells of the hematopoietic system. For these applications, they are the vectors of choice since they provide stable integration into cells that will undergo extensive expansion in vivo. Unfortunately, integration c...

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Detalles Bibliográficos
Autores principales: Shaw, Aaron, Cornetta, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423482/
https://www.ncbi.nlm.nih.gov/pubmed/28548058
http://dx.doi.org/10.3390/biomedicines2010014