Cargando…
A link between transcription fidelity and pausing in vivo
Pausing by RNA polymerase is a major mechanism that regulates transcription elongation but can cause conflicts with fellow RNA polymerases and other cellular machineries. Here, we summarize our recent finding that misincorporation could be a major source of transcription pausing in vivo, and discuss...
Autores principales: | Gamba, Pamela, James, Katherine, Zenkin, Nikolay |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423485/ https://www.ncbi.nlm.nih.gov/pubmed/28072558 http://dx.doi.org/10.1080/21541264.2016.1274812 |
Ejemplares similares
-
Ancient RNA stems that terminate transcription
por: Zenkin, Nikolay
Publicado: (2014) -
Transcript assisted phosphodiester bond hydrolysis by eukaryotic RNA polymerase II
por: Nielsen, Soren, et al.
Publicado: (2013) -
Misincorporation by RNA polymerase is a major source of transcription pausing in vivo
por: James, Katherine, et al.
Publicado: (2017) -
Transcription pausing: biological significance of thermal fluctuations biased by repetitive genomic sequences
por: Imashimizu, Masahiko, et al.
Publicado: (2017) -
Multiple active centers of multi-subunit RNA polymerases
por: Yuzenkova, Yulia, et al.
Publicado: (2012)