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Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

Evidence suggests that disturbances in neurobiological mechanisms of reward and inhibitory control maintain addiction and provoke relapse during abstinence. Abnormalities within the dopamine system may contribute to these disturbances and pharmacologically targeting the D3 dopamine receptor (DRD3) i...

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Detalles Bibliográficos
Autores principales: Murphy, Anna, Nestor, Liam J, McGonigle, John, Paterson, Louise, Boyapati, Venkataramana, Ersche, Karen D, Flechais, Remy, Kuchibatla, Shankar, Metastasio, Antonio, Orban, Csaba, Passetti, Filippo, Reed, Laurence, Smith, Dana, Suckling, John, Taylor, Eleanor, Robbins, Trevor W, Lingford-Hughes, Anne, Nutt, David J, Deakin, John FW, Elliott, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423526/
https://www.ncbi.nlm.nih.gov/pubmed/28042871
http://dx.doi.org/10.1038/npp.2016.289