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Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence
Evidence suggests that disturbances in neurobiological mechanisms of reward and inhibitory control maintain addiction and provoke relapse during abstinence. Abnormalities within the dopamine system may contribute to these disturbances and pharmacologically targeting the D3 dopamine receptor (DRD3) i...
Autores principales: | Murphy, Anna, Nestor, Liam J, McGonigle, John, Paterson, Louise, Boyapati, Venkataramana, Ersche, Karen D, Flechais, Remy, Kuchibatla, Shankar, Metastasio, Antonio, Orban, Csaba, Passetti, Filippo, Reed, Laurence, Smith, Dana, Suckling, John, Taylor, Eleanor, Robbins, Trevor W, Lingford-Hughes, Anne, Nutt, David J, Deakin, John FW, Elliott, Rebecca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423526/ https://www.ncbi.nlm.nih.gov/pubmed/28042871 http://dx.doi.org/10.1038/npp.2016.289 |
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