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Single-molecule protein identification by sub-nanopore sensors

Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a single fragmentation event are often low. In contrast, nanopore t...

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Detalles Bibliográficos
Autores principales: Kolmogorov, Mikhail, Kennedy, Eamonn, Dong, Zhuxin, Timp, Gregory, Pevzner, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423552/
https://www.ncbi.nlm.nih.gov/pubmed/28486472
http://dx.doi.org/10.1371/journal.pcbi.1005356

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