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Single-molecule protein identification by sub-nanopore sensors
Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a single fragmentation event are often low. In contrast, nanopore t...
Autores principales: | Kolmogorov, Mikhail, Kennedy, Eamonn, Dong, Zhuxin, Timp, Gregory, Pevzner, Pavel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423552/ https://www.ncbi.nlm.nih.gov/pubmed/28486472 http://dx.doi.org/10.1371/journal.pcbi.1005356 |
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