Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections

The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with two-stage exchange arthroplasty. The present work reviews t...

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Autor principal: Anagnostakos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423576/
https://www.ncbi.nlm.nih.gov/pubmed/28529862
http://dx.doi.org/10.7150/jbji.16067
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author Anagnostakos, Konstantinos
author_facet Anagnostakos, Konstantinos
author_sort Anagnostakos, Konstantinos
collection PubMed
description The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with two-stage exchange arthroplasty. The present work reviews the current literature about antibiotic-loaded cement spacers and concentrates on the indications for spacer implantation, spacer production details, antibiotic impregnation, pharmacokinetic properties, clinical success, mechanical complications, and systemic safety.
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spelling pubmed-54235762017-05-19 Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections Anagnostakos, Konstantinos J Bone Jt Infect Review The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with two-stage exchange arthroplasty. The present work reviews the current literature about antibiotic-loaded cement spacers and concentrates on the indications for spacer implantation, spacer production details, antibiotic impregnation, pharmacokinetic properties, clinical success, mechanical complications, and systemic safety. Ivyspring International Publisher 2017-01-01 /pmc/articles/PMC5423576/ /pubmed/28529862 http://dx.doi.org/10.7150/jbji.16067 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Anagnostakos, Konstantinos
Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title_full Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title_fullStr Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title_full_unstemmed Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title_short Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections
title_sort therapeutic use of antibiotic-loaded bone cement in the treatment of hip and knee joint infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423576/
https://www.ncbi.nlm.nih.gov/pubmed/28529862
http://dx.doi.org/10.7150/jbji.16067
work_keys_str_mv AT anagnostakoskonstantinos therapeuticuseofantibioticloadedbonecementinthetreatmentofhipandkneejointinfections

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