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The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca(2+) signaling

The non-canonical Wnt/Ca(2+) signaling pathway plays important roles in embryonic development, tissue formation and diseases. However, it is unclear how the Wnt ligand-stimulated, G protein-coupled receptor Frizzled activates phospholipases for calcium release. Here, we report that the zebrafish/hum...

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Detalles Bibliográficos
Autores principales: Gong, Bo, Shen, Weimin, Xiao, Wanghua, Meng, Yaping, Meng, Anming, Jia, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423769/
https://www.ncbi.nlm.nih.gov/pubmed/28463110
http://dx.doi.org/10.7554/eLife.26362