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Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop.

The synaptonemal complex (SC) is an ultrastructurally conserved proteinaceous structure that holds homologous chromosomes together and is required for the stabilization of pairing interactions and the completion of crossover (CO) formation between homologs during meiosis I. Here, we identify a novel...

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Detalles Bibliográficos
Autores principales:	Nadarajan, Saravanapriah, Lambert, Talley J, Altendorfer, Elisabeth, Gao, Jinmin, Blower, Michael D, Waters, Jennifer C, Colaiácovo, Monica P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423773/ https://www.ncbi.nlm.nih.gov/pubmed/28346135 http://dx.doi.org/10.7554/eLife.23437

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