Cargando…

Expression and Correlation of Hypoxia-Inducible Factor-1α (HIF-1α) with Pulmonary Artery Remodeling and Right Ventricular Hypertrophy in Experimental Pulmonary Embolism

BACKGROUND: We investigated the expression of HIF-1α (hypoxia-inducible factor-1α) and its correlations with pulmonary artery remodeling and right ventricular hypertrophy in PE (pulmonary embolism) rats. MATERIAL/METHODS: After the PE rat model was established, the dynamic changes of mPAP (mean pulm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wenjuan, Zhang, Yimei, Lu, Liwen, Wang, Liling, Chen, Mingxin, Hu, Tianyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423885/ https://www.ncbi.nlm.nih.gov/pubmed/28459801 http://dx.doi.org/10.12659/MSM.900354

Ejemplares similares

Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics
por: Chen, Xi, et al.
Publicado: (2019)

Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension
por: Deng, Haiyan, et al.
Publicado: (2022)

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
por: Labrousse-Arias, David, et al.
Publicado: (2016)

Corrigendum to: HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
Publicado: (2017)

Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
por: Paddenberg, Renate, et al.
Publicado: (2007)

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia
por: Chowdhury, Arpita, et al.
Publicado: (2018)

Could HIF-1α be a novel biomarker for the clinical course and treatment of pulmonary embolism?
por: KERGET, Buğra, et al.
Publicado: (2020)

FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia
por: Liu, Ruxia, et al.
Publicado: (2022)

CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension
por: Luo, Yongting, et al.
Publicado: (2019)

Hypoxia-Inducible Factor 1 alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Pathway Participates in Angiogenesis of Myocardial Infarction in Muscone-Treated Mice: Preliminary Study
por: Du, Yingqiang, et al.
Publicado: (2018)

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling
por: Chu, Wenfeng, et al.
Publicado: (2012)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

Effects of Sevoflurane Pretreatment on Myocardial Ischemia-Reperfusion Injury Through the Akt/Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway
por: Dong, Jingwei, et al.
Publicado: (2019)

IL-33-HIF1α Axis in Hypoxic Pulmonary Hypertension
por: Kumar, Rahul, et al.
Publicado: (2018)

Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis
por: Xu, Xiao, et al.
Publicado: (2022)

Altered hypoxia‐inducible factor–1α (HIF‐1α) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN)
por: Makker, Kartikeya, et al.
Publicado: (2019)

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
por: Mawambo, Gaëlle, et al.
Publicado: (2023)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia
por: Li, Hong Lian, et al.
Publicado: (2017)

Publisher Correction: CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension
por: Luo, Yongting, et al.
Publicado: (2019)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients
por: Huang, Yadi, et al.
Publicado: (2018)

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling
por: Angelini, Daniel J, et al.
Publicado: (2013)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
por: Wang, Mengdong, et al.
Publicado: (2023)

VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α
por: Yue, Yiming, et al.
Publicado: (2023)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours
por: Snell, Cameron E., et al.
Publicado: (2014)

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels
por: Fan, Fenling, et al.
Publicado: (2021)

Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta
por: Zhao, Hui, et al.
Publicado: (2020)

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function
por: Knowles, Helen J.
Publicado: (2020)

Twin Resemblance in Muscle HIF-1α Responses to Hypoxia and Exercise
por: Van Thienen, Ruud, et al.
Publicado: (2017)

HIF-1α contributes to hypoxia adaptation of the naked mole rat
por: Xiao, Bang, et al.
Publicado: (2017)

HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
por: Valladares, Katherine Julissa Palma, et al.
Publicado: (2021)

Role of hypoxia inducible factor HIF-1α in heart valves
por: Georgy, Mark, et al.
Publicado: (2023)

Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis
por: Yudoh, Kazuo, et al.
Publicado: (2005)

Characteristics of Pulmonary Vascular Remodeling in a Novel Model of Shunt-Associated Pulmonary Arterial Hypertension
por: Zhang, Mingjie, et al.
Publicado: (2018)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity
por: Vogel, Johannes, et al.
Publicado: (2019)

Hypoxia‐inducible factor (HIF)‐1α‐induced regulation of lung injury in pulmonary aspiration is mediated through NF‐kB
por: Suresh, Madathilparambil V., et al.
Publicado: (2022)

Cardiomyocyte-Specific Overexpression of HEXIM1 Prevents Right Ventricular Hypertrophy in Hypoxia-Induced Pulmonary Hypertension in Mice
por: Yoshikawa, Noritada, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_bg0do9e9ne1gm8ji3fp74nnt12