Double Knockdown of PHD1 and Keap1 Attenuated Hypoxia-Induced Injuries in Hepatocytes

Background and Aims: Hypoxia and oxidative stress contribute toward liver fibrosis. In this experiment, we used small hairpin RNA (shRNA) to interfere with the intracellular oxygen sensor—prolyl hydroxylase 1 (PHD1) and the intracellular oxidative stress sensor—kelch-like ECH associated protein 1 (K...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Li, Yiping, Liu, Lei, Wang, Zhi, Shi, Chuanbing, Cheng, Zhengyuan, Zhang, Xiaoyi, Ding, Fengan, Chen, Ping Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423937/
https://www.ncbi.nlm.nih.gov/pubmed/28539891
http://dx.doi.org/10.3389/fphys.2017.00291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423937/
https://www.ncbi.nlm.nih.gov/pubmed/28539891
http://dx.doi.org/10.3389/fphys.2017.00291

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