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Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

Nicotinic acid (NiAc) is a potent inhibitor of adipose tissue lipolysis. Acute administration results in a rapid reduction of plasma free fatty acid (FFA) concentrations. Sustained NiAc exposure is associated with tolerance development (drug resistance) and complete adaptation (FFA returning to pret...

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Detalles Bibliográficos
Autores principales:	Andersson, Robert, Kroon, Tobias, Almquist, Joachim, Jirstrand, Mats, Oakes, Nicholas D., Evans, Neil D., Chappel, Michael J., Gabrielsson, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424002/ https://www.ncbi.nlm.nih.gov/pubmed/28224315 http://dx.doi.org/10.1007/s10928-017-9512-6

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