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Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9

Imaging chromatin dynamics is crucial to understand genome organization and its role in transcriptional regulation. Recently, the RNA-guidable feature of CRISPR-Cas9 has been utilized for imaging of chromatin within live cells. However, these methods are mostly applicable to highly repetitive region...

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Detalles Bibliográficos
Autores principales:	Qin, Peiwu, Parlak, Mahmut, Kuscu, Cem, Bandaria, Jigar, Mir, Mustafa, Szlachta, Karol, Singh, Ritambhara, Darzacq, Xavier, Yildiz, Ahmet, Adli, Mazhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424063/ https://www.ncbi.nlm.nih.gov/pubmed/28290446 http://dx.doi.org/10.1038/ncomms14725

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