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Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma

It is largely recognized that fibroblast activation protein (FAP) is expressed in cancer-associated fibroblasts (CAFs) of many human carcinomas. Furthermore, FAP was recently also reported to be expressed in carcinoma cells of the breast, stomach, pancreatic ductal adenocarcinoma, colorectum, and ut...

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Detalles Bibliográficos
Autores principales: Wang, H, Wu, Q, Liu, Z, Luo, X, Fan, Y, Liu, Y, Zhang, Y, Hua, S, Fu, Q, Zhao, M, Chen, Y, Fang, W, Lv, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424105/
https://www.ncbi.nlm.nih.gov/pubmed/24722280
http://dx.doi.org/10.1038/cddis.2014.122