Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib

Microtubule-binding agents, such as taxanes and vinca alkaloids, are used in the treatment of cancer. The limitations of these treatments, such as resistance to therapy and the need for intravenous administration, have encouraged the development of new agents. MPT0B271 (N-[1-(4-Methoxy-benzenesulfon...

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Detalles Bibliográficos
Autores principales: Tsai, A-C, Wang, C-Y, Liou, J-P, Pai, H-C, Hsiao, C-J, Chang, J-Y, Wang, J-C, Teng, C-M, Pan, S-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424107/
https://www.ncbi.nlm.nih.gov/pubmed/24722287
http://dx.doi.org/10.1038/cddis.2014.128

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