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Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer

Dysregulated Notch signaling has a critical role in the tumorigenesis. Jagged1, a Notch ligand, is overexpressed in various human cancers. Recent studies revealed the involvement of Jagged1 in colorectal cancer (CRC) development. These basic studies provide a promising potential for inhibition of th...

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Detalles Bibliográficos
Autores principales:	Dai, Y, Wilson, G, Huang, B, Peng, M, Teng, G, Zhang, D, Zhang, R, Ebert, M P A, Chen, J, Wong, B C Y, Chan, K W, George, J, Qiao, L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424114/ https://www.ncbi.nlm.nih.gov/pubmed/24722295 http://dx.doi.org/10.1038/cddis.2014.137

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