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The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
O-GlcNAcylation has been implicated in the tumorigenesis of various tissue origins, but its function in liver tumorigenesis is not clear. Here, we demonstrate that O-GlcNAcylation can enhance the expression, stability and function of Yes-associated protein (YAP), the downstream transcriptional regul...
Autores principales: | Zhang, Xiao, Qiao, Yongxia, Wu, Qi, Chen, Yan, Zou, Shaowu, Liu, Xiangfan, Zhu, Guoqing, Zhao, Yinghui, Chen, Yuxin, Yu, Yongchun, Pan, Qiuhui, Wang, Jiayi, Sun, Fenyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424161/ https://www.ncbi.nlm.nih.gov/pubmed/28474680 http://dx.doi.org/10.1038/ncomms15280 |
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