Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism

Heparin-induced thrombocytopenia (HIT) is a prothrombotic adverse drug reaction in which heparin forms complexes with platelet factor 4 forming neoantigens that are recognized by autoantibodies. Antiphospholipid syndrome (APS) is similar to HIT in that it is mediated by autoantibodies that are also...

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Autores principales: Adediran, Samuel, Agostino, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424171/
https://www.ncbi.nlm.nih.gov/pubmed/28589046
http://dx.doi.org/10.1155/2017/3423548
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author Adediran, Samuel
Agostino, Nicole
author_facet Adediran, Samuel
Agostino, Nicole
author_sort Adediran, Samuel
collection PubMed
description Heparin-induced thrombocytopenia (HIT) is a prothrombotic adverse drug reaction in which heparin forms complexes with platelet factor 4 forming neoantigens that are recognized by autoantibodies. Antiphospholipid syndrome (APS) is similar to HIT in that it is mediated by autoantibodies that are also prothrombotic. We present a case of rare coexistence of antiphospholipid antibody syndrome and heparin-induced thrombocytopenia.
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spelling pubmed-54241712017-06-06 Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism Adediran, Samuel Agostino, Nicole Case Rep Hematol Case Report Heparin-induced thrombocytopenia (HIT) is a prothrombotic adverse drug reaction in which heparin forms complexes with platelet factor 4 forming neoantigens that are recognized by autoantibodies. Antiphospholipid syndrome (APS) is similar to HIT in that it is mediated by autoantibodies that are also prothrombotic. We present a case of rare coexistence of antiphospholipid antibody syndrome and heparin-induced thrombocytopenia. Hindawi 2017 2017-04-26 /pmc/articles/PMC5424171/ /pubmed/28589046 http://dx.doi.org/10.1155/2017/3423548 Text en Copyright © 2017 Samuel Adediran and Nicole Agostino. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Adediran, Samuel
Agostino, Nicole
Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title_full Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title_fullStr Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title_full_unstemmed Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title_short Coexistence of Antiphospholipid Syndrome and Heparin-Induced Thrombocytopenia in a Patient with Recurrent Venous Thromboembolism
title_sort coexistence of antiphospholipid syndrome and heparin-induced thrombocytopenia in a patient with recurrent venous thromboembolism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424171/
https://www.ncbi.nlm.nih.gov/pubmed/28589046
http://dx.doi.org/10.1155/2017/3423548
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AT agostinonicole coexistenceofantiphospholipidsyndromeandheparininducedthrombocytopeniainapatientwithrecurrentvenousthromboembolism

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