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Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis

BACKGROUND: DIRAS1 is a new member of the Ras gene family. It was described as a potential tumor suppressor in human glioblastomas and esophageal cancer. The role of DIRAS1 in colorectal cancer remains unclear. METHODS: To explore the epigenetic changes and function of DIRAS1 in human colorectal can...

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Detalles Bibliográficos
Autores principales: Zheng, Ruipan, Gao, Dan, He, Tao, Zhang, Meiying, Zhang, Xiaomei, Linghu, Enqiang, Wei, Lixin, Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424295/
https://www.ncbi.nlm.nih.gov/pubmed/28491151
http://dx.doi.org/10.1186/s13148-017-0348-0