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Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis
BACKGROUND: DIRAS1 is a new member of the Ras gene family. It was described as a potential tumor suppressor in human glioblastomas and esophageal cancer. The role of DIRAS1 in colorectal cancer remains unclear. METHODS: To explore the epigenetic changes and function of DIRAS1 in human colorectal can...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424295/ https://www.ncbi.nlm.nih.gov/pubmed/28491151 http://dx.doi.org/10.1186/s13148-017-0348-0 |