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MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway

BACKGROUND: Cardiomyocyte apoptosis is a common pathological manifestation that occurs in several heart diseases. This study aimed to explore the mechanism of microRNA-486 (miR-486) in cardiomyocyte apoptosis by interfering with the p53-activated BCL-2 associated mitochondrial pathway. METHODS: miR-...

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Detalles Bibliográficos
Autores principales:	Sun, Yuhan, Su, Qiang, Li, Lang, Wang, Xiantao, Lu, Yuanxi, Liang, Jiabao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424355/ https://www.ncbi.nlm.nih.gov/pubmed/28486954 http://dx.doi.org/10.1186/s12872-017-0549-7

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