An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors

BACKGROUND: Epithelial ovarian carcinomas encompass a heterogeneous group of diseases with a poor 5-year survival rate. Serous carcinoma is the most common type. Most FDA-approved serum tumor markers are glycoproteins. These glycoproteins on cell surface or shed into the bloodstream could serve as t...

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Detalles Bibliográficos
Autores principales: Li, Qing Kay, Shah, Punit, Tian, Yuan, Hu, Yingwei, Roden, Richard B. S., Zhang, Hui, Chan, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424371/
https://www.ncbi.nlm.nih.gov/pubmed/28491011
http://dx.doi.org/10.1186/s12014-017-9152-2

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