Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

BACKGROUND: The stem cell-based therapies for intervertebral disc degeneration have been widely studied. However, the mechanisms of mesenchymal stem cells interacting with intervertebral disc cells, such as nucleus pulposus cells (NPCs), remain unknown. Exosomes as a vital paracrine mechanism in cel...

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Detalles Bibliográficos
Autores principales: Lu, Kang, Li, Hai-yin, Yang, Kuang, Wu, Jun-long, Cai, Xiao-wei, Zhou, Yue, Li, Chang-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424403/
https://www.ncbi.nlm.nih.gov/pubmed/28486958
http://dx.doi.org/10.1186/s13287-017-0563-9

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