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Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction
[Image: see text] Ammonia in the tetrazole Ugi variation together with α-amino acid methyl ester-derived isocyanides provides tetrazolopiperidinones in good to high yields in one pot. The scope and limitations of this reaction were investigated by performing >70 reactions. The scaffold is useful...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424440/ https://www.ncbi.nlm.nih.gov/pubmed/28240545 http://dx.doi.org/10.1021/acscombsci.7b00033 |