Cargando…

CD19 Isoforms Enabling Resistance to CART-19 Immunotherapy Are Expressed in B-ALL Patients at Initial Diagnosis

B-cell acute lymphoblastic leukemia (B-ALL) is the commonest childhood cancer and the prognosis of children with relapsed or therapy refractory disease remains a challenge. Treatment with chimeric antigen receptor-modified T cells targeting the CD19 antigen (CART-19 therapy) has been presented as a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fischer, Jeannette, Paret, Claudia, El Malki, Khalifa, Alt, Francesca, Wingerter, Arthur, Neu, Marie A., Kron, Bettina, Russo, Alexandra, Lehmann, Nadine, Roth, Lea, Fehr, Eva-M., Attig, Sebastian, Hohberger, Alexander, Kindler, Thomas, Faber, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424577/ https://www.ncbi.nlm.nih.gov/pubmed/28441264 http://dx.doi.org/10.1097/CJI.0000000000000169

Ejemplares similares

Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALL
por: Ziegler, Nicole, et al.
Publicado: (2023)

Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy
por: Paret, Claudia, et al.
Publicado: (2016)

Tumor Lipids of Pediatric Papillary Renal Cell Carcinoma Stimulate Unconventional T Cells
por: Lehmann, Nadine, et al.
Publicado: (2020)

Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma
por: Beck, Olaf, et al.
Publicado: (2020)

Identification of an Immunogenic Medulloblastoma-Specific Fusion Involving EPC2 and GULP1
por: Paret, Claudia, et al.
Publicado: (2021)

HGG-03. THE GLYCOSPHINGOLIPIDS METABOLISM IS A NOVEL TARGET IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMA
por: Paret, Claudia, et al.
Publicado: (2021)

Exploiting Gangliosides for the Therapy of Ewing’s Sarcoma and H3K27M-Mutant Diffuse Midline Glioma
por: Wingerter, Arthur, et al.
Publicado: (2021)

Benefits of Exercise Training for Children and Adolescents Undergoing Cancer Treatment: Results From the Randomized Controlled MUCKI Trial
por: Stössel, Sandra, et al.
Publicado: (2020)

Exercise reduces systemic immune inflammation index (SII) in childhood cancer patients
por: Winker, Matteo, et al.
Publicado: (2021)

Personalized therapy: CNS HGNET-BCOR responsiveness to arsenic trioxide combined with radiotherapy
por: Paret, Claudia, et al.
Publicado: (2017)

IGF1R Is a Potential New Therapeutic Target for HGNET-BCOR Brain Tumor Patients
por: Vewinger, Nadine, et al.
Publicado: (2019)

Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor
por: Russo, Alexandra, et al.
Publicado: (2019)

Glucosylceramide Synthase Inhibitors Induce Ceramide Accumulation and Sensitize H3K27 Mutant Diffuse Midline Glioma to Irradiation
por: El Malki, Khalifa, et al.
Publicado: (2023)

High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance
por: Cortés-López, Mariela, et al.
Publicado: (2022)

Characterization of the Two CART Genes (CART1 and CART2) in Chickens (Gallus gallus)
por: Cai, Guoqing, et al.
Publicado: (2015)

GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype
por: Paret, Claudia, et al.
Publicado: (2022)

Research on COVID-19 therapy: Putting the cart alongside the horse
por: Duvignaud, Alexandre, et al.
Publicado: (2021)

Extended Ganglion Cell Layer Thickness Deviation Maps With OCT in Glaucoma Diagnosis
por: Lehmann, Paul, et al.
Publicado: (2021)

Polarization response of nanowires à la carte
por: Casadei, Alberto, et al.
Publicado: (2015)

STAT3 isoforms differentially affect ACE2 expression: A potential target for COVID‐19 therapy
por: Shamir, Inbal, et al.
Publicado: (2020)

Cartes postales électroniques
Publicado: (1987)

In vivo CART cell imaging: Paving the way for success in CART cell therapy
por: Sakemura, Reona, et al.
Publicado: (2021)

The apple cart : a political extravaganza /
por: Shaw, Bernard, 1856-1950
Publicado: (1932)

Die „DOG 2020 online“ – erstmals im von-Graefe-Jahr
por: Hohberger, Bettina
Publicado: (2021)

Les dernières cartes : roman /
por: Schnitzler, Arthur, 1862-1931
Publicado: (1953)

Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro
por: Ledererova, Aneta, et al.
Publicado: (2021)

The cart and the trumpet : the plays of George Bernard Shaw
por: Valency, Maurice
Publicado: (1973)

Jeu de cartes Orpheus ; Agon /
por: Stravinsky, Igor, 1882-1971
Publicado: (1994)

Cartes de Carles Riba
Publicado: (1990)

The boy wit a cart/
por: Fry Christopher

CARTing Away Cardiac Fibrosis
por: Epstein, Jonathan A.
Publicado: (2020)

Efficacy of second CAR-T (CART2) infusion limited by poor CART expansion and antigen modulation
por: Holland, Elizabeth M, et al.
Publicado: (2022)

Physical phenotype of blood cells is altered in COVID-19
por: Kubánková, Markéta, et al.
Publicado: (2021)

Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19
por: Asnani, Mukta, et al.
Publicado: (2019)

La carte d'identité : roman
por: Adiaffi, Jean-Marie
Publicado: (1980)

Adoptive Immune Responses to Sars-Cov2 Vaccination in CART19 Treated Patients
por: Parvathaneni, Kalpana, et al.
Publicado: (2021)

Pushing or clicking the grocery cart? Health and economic concerns during the COVID‐19 pandemic
por: Xu, Yilan, et al.
Publicado: (2022)

Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy
por: Nunez, Daniel, et al.
Publicado: (2023)

DESY : joue la carte TESLA
Publicado: (2001)

Hugo et les cartes magiques
por: Favret, Catherine
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_cq8orcvd2dbr6sb30phuthrc21