Cargando…
THE PATHOPHYSIOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION AND THE COMPLEMENT PATHWAY AS A THERAPEUTIC TARGET
PURPOSE: Geographic atrophy (GA) is an advanced, vision-threatening form of age-related macular degeneration (AMD) affecting approximately five million individuals worldwide. To date, there are no approved therapeutics for GA treatment; however, several are in clinical trials. This review focuses on...
Autores principales: | Boyer, David S., Schmidt-Erfurth, Ursula, van Lookeren Campagne, Menno, Henry, Erin C., Brittain, Christopher |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Retina
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424580/ https://www.ncbi.nlm.nih.gov/pubmed/27902638 http://dx.doi.org/10.1097/IAE.0000000000001392 |
Ejemplares similares
-
C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
por: Yednock, Ted, et al.
Publicado: (2022) -
A Review of Completed and Ongoing Complement Inhibitor Trials for Geographic Atrophy Secondary to Age-Related Macular Degeneration
por: Halawa, Omar A., et al.
Publicado: (2021) -
CLINICOPATHOLOGIC CORRELATION OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION
por: Li, Miaoling, et al.
Publicado: (2019) -
Plasma biomarkers of the amyloid pathway are associated with geographic atrophy secondary to age-related macular degeneration
por: Lashkari, Kameran, et al.
Publicado: (2020) -
Clinical validation for automated geographic atrophy monitoring on OCT under complement inhibitory treatment
por: Mai, Julia, et al.
Publicado: (2023)