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In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case

Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metas...

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Autores principales: Merat, Rastine, Boehncke, Wolf-Henning, Kaya, Gürkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Derm101.com 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424663/
https://www.ncbi.nlm.nih.gov/pubmed/28515994
http://dx.doi.org/10.5826/dpc.0702a10
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author Merat, Rastine
Boehncke, Wolf-Henning
Kaya, Gürkan
author_facet Merat, Rastine
Boehncke, Wolf-Henning
Kaya, Gürkan
author_sort Merat, Rastine
collection PubMed
description Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metastatic disease and correspond to the residual melanophage granuloma that persists after tumor tissues undergo complete necrosis. Reflectance confocal microscopy (RCM) is a non-invasive technique that allows the exploration of the superficial dermis. Here, we present the case of a patient in whom numerous post-ILP limb residual pigmented lesions were explored using combined RCM and histological examination of sample lesions and could be characterized as non-active. This approach allowed us to avoid additional excisions.
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spelling pubmed-54246632017-05-17 In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case Merat, Rastine Boehncke, Wolf-Henning Kaya, Gürkan Dermatol Pract Concept Articles Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metastatic disease and correspond to the residual melanophage granuloma that persists after tumor tissues undergo complete necrosis. Reflectance confocal microscopy (RCM) is a non-invasive technique that allows the exploration of the superficial dermis. Here, we present the case of a patient in whom numerous post-ILP limb residual pigmented lesions were explored using combined RCM and histological examination of sample lesions and could be characterized as non-active. This approach allowed us to avoid additional excisions. Derm101.com 2017-04-30 /pmc/articles/PMC5424663/ /pubmed/28515994 http://dx.doi.org/10.5826/dpc.0702a10 Text en ©2017 Merat et al This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Articles
Merat, Rastine
Boehncke, Wolf-Henning
Kaya, Gürkan
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title_full In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title_fullStr In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title_full_unstemmed In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title_short In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
title_sort in vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. report of a case
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424663/
https://www.ncbi.nlm.nih.gov/pubmed/28515994
http://dx.doi.org/10.5826/dpc.0702a10
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