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PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION

BACKGROUND: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. AIM: To analyze the correlation between CTV and GW in an adult LD...

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Autores principales: PINHEIRO, Rafael S., CRUZ-JR, Ruy J., ANDRAUS, Wellington, DUCATTI, Liliana, MARTINO, Rodrigo B., NACIF, Lucas S., ROCHA-SANTOS, Vinicius, ARANTES, Rubens M, LAI, Quirino, IBUKI, Felicia S., ROCHA, Manoel S., D´ALBUQUERQUE, Luiz A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424685/
https://www.ncbi.nlm.nih.gov/pubmed/28489167
http://dx.doi.org/10.1590/0102-6720201700010011
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author PINHEIRO, Rafael S.
CRUZ-JR, Ruy J.
ANDRAUS, Wellington
DUCATTI, Liliana
MARTINO, Rodrigo B.
NACIF, Lucas S.
ROCHA-SANTOS, Vinicius
ARANTES, Rubens M
LAI, Quirino
IBUKI, Felicia S.
ROCHA, Manoel S.
D´ALBUQUERQUE, Luiz A. C.
author_facet PINHEIRO, Rafael S.
CRUZ-JR, Ruy J.
ANDRAUS, Wellington
DUCATTI, Liliana
MARTINO, Rodrigo B.
NACIF, Lucas S.
ROCHA-SANTOS, Vinicius
ARANTES, Rubens M
LAI, Quirino
IBUKI, Felicia S.
ROCHA, Manoel S.
D´ALBUQUERQUE, Luiz A. C.
author_sort PINHEIRO, Rafael S.
collection PubMed
description BACKGROUND: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. AIM: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. METHODS: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. RESULTS: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r(2)=0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 - 0.99 (p<0.0001). CONCLUSION: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82.
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spelling pubmed-54246852017-05-15 PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION PINHEIRO, Rafael S. CRUZ-JR, Ruy J. ANDRAUS, Wellington DUCATTI, Liliana MARTINO, Rodrigo B. NACIF, Lucas S. ROCHA-SANTOS, Vinicius ARANTES, Rubens M LAI, Quirino IBUKI, Felicia S. ROCHA, Manoel S. D´ALBUQUERQUE, Luiz A. C. Arq Bras Cir Dig Original Article BACKGROUND: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. AIM: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. METHODS: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. RESULTS: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r(2)=0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 - 0.99 (p<0.0001). CONCLUSION: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82. Colégio Brasileiro de Cirurgia Digestiva 2017 /pmc/articles/PMC5424685/ /pubmed/28489167 http://dx.doi.org/10.1590/0102-6720201700010011 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
PINHEIRO, Rafael S.
CRUZ-JR, Ruy J.
ANDRAUS, Wellington
DUCATTI, Liliana
MARTINO, Rodrigo B.
NACIF, Lucas S.
ROCHA-SANTOS, Vinicius
ARANTES, Rubens M
LAI, Quirino
IBUKI, Felicia S.
ROCHA, Manoel S.
D´ALBUQUERQUE, Luiz A. C.
PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title_full PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title_fullStr PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title_full_unstemmed PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title_short PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION
title_sort preoperative computed tomography volumetry and graft weight estimation in adult living donor liver transplantation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424685/
https://www.ncbi.nlm.nih.gov/pubmed/28489167
http://dx.doi.org/10.1590/0102-6720201700010011
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