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THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW

INTRODUCTION: Liver transplantation is intended to increase the survival of patients with chronic liver disease in terminal phase, as well as improved quality of life. Since the first transplant until today many changes have occurred in the organ allocation system. OBJECTIVE: To review the literatur...

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Autores principales: de MORAES, Ana Claudia Oliveira, de OLIVEIRA, Priscilla Caroliny, da FONSECA-NETO, Olival Cirilo Lucena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424692/
https://www.ncbi.nlm.nih.gov/pubmed/28489174
http://dx.doi.org/10.1590/0102-6720201700010018
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author de MORAES, Ana Claudia Oliveira
de OLIVEIRA, Priscilla Caroliny
da FONSECA-NETO, Olival Cirilo Lucena
author_facet de MORAES, Ana Claudia Oliveira
de OLIVEIRA, Priscilla Caroliny
da FONSECA-NETO, Olival Cirilo Lucena
author_sort de MORAES, Ana Claudia Oliveira
collection PubMed
description INTRODUCTION: Liver transplantation is intended to increase the survival of patients with chronic liver disease in terminal phase, as well as improved quality of life. Since the first transplant until today many changes have occurred in the organ allocation system. OBJECTIVE: To review the literature on the Model for End-stage Liver Disease (MELD) and analyze its correlation with survival after liver transplantation. METHOD: An integrative literature review in Lilacs, SciELO, and Pubmed in October 2015, was realized. Were included eight studies related to the MELD score and its impact on liver transplant. RESULTS: There was predominance of transplants in male between 45-55 y. The main indications were hepatitis C, hepatocellular carcinoma and alcoholic cirrhosis. The most important factors post-surgery were related to the MELD score, the recipient age, expanded donor criteria and hemotransfusion. CONCLUSION: The MELD system reduced the death rate in patients waiting for a liver transplant. However, this score by itself is not a good predictor of survival after liver transplantation.
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spelling pubmed-54246922017-05-15 THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW de MORAES, Ana Claudia Oliveira de OLIVEIRA, Priscilla Caroliny da FONSECA-NETO, Olival Cirilo Lucena Arq Bras Cir Dig Review Article INTRODUCTION: Liver transplantation is intended to increase the survival of patients with chronic liver disease in terminal phase, as well as improved quality of life. Since the first transplant until today many changes have occurred in the organ allocation system. OBJECTIVE: To review the literature on the Model for End-stage Liver Disease (MELD) and analyze its correlation with survival after liver transplantation. METHOD: An integrative literature review in Lilacs, SciELO, and Pubmed in October 2015, was realized. Were included eight studies related to the MELD score and its impact on liver transplant. RESULTS: There was predominance of transplants in male between 45-55 y. The main indications were hepatitis C, hepatocellular carcinoma and alcoholic cirrhosis. The most important factors post-surgery were related to the MELD score, the recipient age, expanded donor criteria and hemotransfusion. CONCLUSION: The MELD system reduced the death rate in patients waiting for a liver transplant. However, this score by itself is not a good predictor of survival after liver transplantation. Colégio Brasileiro de Cirurgia Digestiva 2017 /pmc/articles/PMC5424692/ /pubmed/28489174 http://dx.doi.org/10.1590/0102-6720201700010018 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Review Article
de MORAES, Ana Claudia Oliveira
de OLIVEIRA, Priscilla Caroliny
da FONSECA-NETO, Olival Cirilo Lucena
THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title_full THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title_fullStr THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title_full_unstemmed THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title_short THE IMPACT OF THE MELD SCORE ON LIVER TRANSPLANT ALLOCATION AND RESULTS: AN INTEGRATIVE REVIEW
title_sort impact of the meld score on liver transplant allocation and results: an integrative review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424692/
https://www.ncbi.nlm.nih.gov/pubmed/28489174
http://dx.doi.org/10.1590/0102-6720201700010018
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