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Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution
Label-free detection of single-nucleotides was performed by fast tunneling current measurements in a polar solvent at 1 MHz sampling rate using SiO(2)-protected Au nanoprobes. Short current spikes were observed, suggestive of trapping/detrapping of individual nucleotides between the nanoelectrodes....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424762/ https://www.ncbi.nlm.nih.gov/pubmed/28420199 http://dx.doi.org/10.3390/s17040885 |