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Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics()
Loss of function mutations of the protein MICU1, a regulator of mitochondrial Ca(2 +) uptake, cause a neuronal and muscular disorder characterised by impaired cognition, muscle weakness and an extrapyramidal motor disorder. We have shown previously that MICU1 mutations cause increased resting mitoch...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424885/ https://www.ncbi.nlm.nih.gov/pubmed/28132899 http://dx.doi.org/10.1016/j.bbamcr.2017.01.015 |