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Accelerated epigenetic aging in Werner syndrome
Individuals suffering from Werner syndrome (WS) exhibit many clinical signs of accelerated aging. While the underlying constitutional mutation leads to accelerated rates of DNA damage, it is not yet known whether WS is also associated with an increased epigenetic age according to a DNA methylation b...
Autores principales: | Maierhofer, Anna, Flunkert, Julia, Oshima, Junko, Martin, George M., Haaf, Thomas, Horvath, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425119/ https://www.ncbi.nlm.nih.gov/pubmed/28377537 http://dx.doi.org/10.18632/aging.101217 |
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