Human β-defensin-2 production upon viral and bacterial co-infection is attenuated in COPD

Viral-bacterial co-infections are associated with severe exacerbations of COPD. Epithelial antimicrobial peptides, including human β-defensin-2 (HBD-2), are integral to innate host defenses. In this study, we examined how co-infection of airway epithelial cells with rhinovirus and Pseudomonas aerugi...

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Detalles Bibliográficos
Autores principales: Arnason, Jason W., Murphy, James C., Kooi, Cora, Wiehler, Shahina, Traves, Suzanne L., Shelfoon, Christopher, Maciejewski, Barbara, Dumonceaux, Curtis J., Lewenza, W. Shawn, Proud, David, Leigh, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425185/
https://www.ncbi.nlm.nih.gov/pubmed/28489911
http://dx.doi.org/10.1371/journal.pone.0175963

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