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Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling

Burkholderia pseudomallei (Bp) causes the disease melioidosis. The main cause of mortality in this disease is septic shock triggered by the host responding to lipopolysaccharide (LPS) components of the Gram-negative outer membrane. Bp LPS is thought to be a weak inducer of the host immune system. LP...

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Detalles Bibliográficos
Autores principales: Norris, Michael H., Schweizer, Herbert P., Tuanyok, Apichai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425228/
https://www.ncbi.nlm.nih.gov/pubmed/28453531
http://dx.doi.org/10.1371/journal.pntd.0005571