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Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes
Deficiency in cerebral amyloid β-protein (Aβ) clearance is implicated in the pathogenesis of the common late-onset forms of Alzheimer’s disease (AD). Accumulation of misfolded Aβ in the brain is believed to be a net result of imbalance between its production and removal. This in turn may trigger neu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425508/ https://www.ncbi.nlm.nih.gov/pubmed/28197669 http://dx.doi.org/10.1007/s00018-017-2463-7 |