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Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes

Deficiency in cerebral amyloid β-protein (Aβ) clearance is implicated in the pathogenesis of the common late-onset forms of Alzheimer’s disease (AD). Accumulation of misfolded Aβ in the brain is believed to be a net result of imbalance between its production and removal. This in turn may trigger neu...

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Detalles Bibliográficos
Autores principales: Zuroff, Leah, Daley, David, Black, Keith L., Koronyo-Hamaoui, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425508/
https://www.ncbi.nlm.nih.gov/pubmed/28197669
http://dx.doi.org/10.1007/s00018-017-2463-7