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Modeling Developmental and Tumorigenic Aspects of Trilateral Retinoblastoma via Human Embryonic Stem Cells

Human embryonic stem cells (hESCs) provide a platform for studying human development and understanding mechanisms underlying diseases. Retinoblastoma-1 (RB1) is a key regulator of cell cycling, of which biallelic inactivation initiates retinoblastoma, the most common congenital intraocular malignanc...

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Detalles Bibliográficos
Autores principales:	Avior, Yishai, Lezmi, Elyad, Yanuka, Dorit, Benvenisty, Nissim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425613/ https://www.ncbi.nlm.nih.gov/pubmed/28392220 http://dx.doi.org/10.1016/j.stemcr.2017.03.005

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