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Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization

Hematopoietic stem/progenitor cells (HSPCs) are formed during ontogeny from hemogenic endothelium in the ventral wall of the dorsal aorta (VDA). Critically, the cellular mechanism(s) allowing HSPC egress and migration to secondary niches are incompletely understood. Matrix metalloproteinases (MMPs)...

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Detalles Bibliográficos
Autores principales:	Theodore, Lindsay N., Hagedorn, Elliott J., Cortes, Mauricio, Natsuhara, Kelsey, Liu, Sarah Y., Perlin, Julie R., Yang, Song, Daily, Madeleine L., Zon, Leonard I., North, Trista E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425629/ https://www.ncbi.nlm.nih.gov/pubmed/28416284 http://dx.doi.org/10.1016/j.stemcr.2017.03.016

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