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iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells
Regulatory dendritic cell (DCregs)-based immunotherapy is a potential therapeutic tool for transplant rejection. We generated DCregs from murine induced pluripotent stem cells (iPSCs), which could remain in a “stable immature stage” even under strong stimulation. Harnessing this characteristic, we h...
Autores principales: | Cai, Songjie, Hou, Jiangang, Fujino, Masayuki, Zhang, Qi, Ichimaru, Naotsugu, Takahara, Shiro, Araki, Ryoko, Lu, Lina, Chen, Ji-Mei, Zhuang, Jian, Zhu, Ping, Li, Xiao-Kang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425686/ https://www.ncbi.nlm.nih.gov/pubmed/28434942 http://dx.doi.org/10.1016/j.stemcr.2017.03.020 |
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