Engineering potent long-acting variants of the Wnt inhibitor DKK2

Wnt signaling pathways are required for a wide variety of biological processes ranging from embryonic development to tissue repair and regeneration. Dickkopf-2 (DKK2) is classically defined as a canonical Wnt inhibitor, though it may play a role in activating non-canonical Wnt pathways in the contex...

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Detalles Bibliográficos
Autores principales: Sopko, Richelle, Mugford, Joshua W., Lehmann, Andreas, Shapiro, Renée I., Rushe, Mia, Kulkarni, Abhishek, Worrall, Joseph, Amatucci, Joseph, Wen, Dingyi, Pederson, Nels E., Minesinger, Brenda K., Arndt, Joseph W., Pepinsky, Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425732/
https://www.ncbi.nlm.nih.gov/pubmed/28180900
http://dx.doi.org/10.1093/protein/gzx007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425732/
https://www.ncbi.nlm.nih.gov/pubmed/28180900
http://dx.doi.org/10.1093/protein/gzx007

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