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Engineering potent long-acting variants of the Wnt inhibitor DKK2

Wnt signaling pathways are required for a wide variety of biological processes ranging from embryonic development to tissue repair and regeneration. Dickkopf-2 (DKK2) is classically defined as a canonical Wnt inhibitor, though it may play a role in activating non-canonical Wnt pathways in the contex...

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Detalles Bibliográficos
Autores principales:	Sopko, Richelle, Mugford, Joshua W., Lehmann, Andreas, Shapiro, Renée I., Rushe, Mia, Kulkarni, Abhishek, Worrall, Joseph, Amatucci, Joseph, Wen, Dingyi, Pederson, Nels E., Minesinger, Brenda K., Arndt, Joseph W., Pepinsky, Blake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425732/ https://www.ncbi.nlm.nih.gov/pubmed/28180900 http://dx.doi.org/10.1093/protein/gzx007

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