Efficient Recreation of t(11;22) EWSR1-FLI1(+) in Human Stem Cells Using CRISPR/Cas9

Efficient methodologies for recreating cancer-associated chromosome translocations are in high demand as tools for investigating how such events initiate cancer. The CRISPR/Cas9 system has been used to reconstruct the genetics of these complex rearrangements at native loci while maintaining the arch...

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Detalles Bibliográficos
Autores principales: Torres-Ruiz, Raul, Martinez-Lage, Marta, Martin, Maria C., Garcia, Aida, Bueno, Clara, Castaño, Julio, Ramirez, Juan C., Menendez, Pablo, Cigudosa, Juan C., Rodriguez-Perales, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425785/
https://www.ncbi.nlm.nih.gov/pubmed/28494941
http://dx.doi.org/10.1016/j.stemcr.2017.04.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425785/
https://www.ncbi.nlm.nih.gov/pubmed/28494941
http://dx.doi.org/10.1016/j.stemcr.2017.04.014

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