Cargando…

Long-term safety of once-daily, dual-release hydrocortisone in patients with adrenal insufficiency: a phase 3b, open-label, extension study

OBJECTIVE: To investigate the long-term safety and tolerability of a once-daily, dual-release hydrocortisone (DR-HC) tablet as oral glucocorticoid replacement therapy in patients with primary adrenal insufficiency (AI). DESIGN: Prospective, open-label, multicenter, 5-year extension study of DR-HC co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nilsson, Anna G, Bergthorsdottir, Ragnhildur, Burman, Pia, Dahlqvist, Per, Ekman, Bertil, Engström, Britt Edén, Ragnarsson, Oskar, Skrtic, Stanko, Wahlberg, Jeanette, Achenbach, Heinrich, Uddin, Sharif, Marelli, Claudio, Johannsson, Gudmundur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2017
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425941/ https://www.ncbi.nlm.nih.gov/pubmed/28292927 http://dx.doi.org/10.1530/EJE-17-0067

Ejemplares similares

Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone
por: Espiard, Stéphanie, et al.
Publicado: (2020)

Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency
por: Nilsson, A G, et al.
Publicado: (2014)

Achieving a physiological cortisol profile with once-daily dual-release hydrocortisone: a pharmacokinetic study
por: Johannsson, Gudmundur, et al.
Publicado: (2016)

SAT302 Circulating And Urinary Metabolites Associated With Total Exposure Of Cortisol And Cortisol Time Profile
por: McQueen, Johanna, et al.
Publicado: (2023)

OR30-06 Hospitalisation, Intensive Care And Death Due To COVID-19 In Swedish Patients With Adrenal Insufficiency
por: Bergthorsdottir, Ragnhildur, et al.
Publicado: (2023)

Psychotropic Drugs in Patients with Cushing’s Disease Before Diagnosis and at Long-Term Follow-Up: A Nationwide Study
por: Bengtsson, Daniel, et al.
Publicado: (2021)

Metabolic Effects of Cortisone Acetate vs Hydrocortisone in Patients With Secondary Adrenal Insufficiency
por: Ekstrand, Elise, et al.
Publicado: (2020)

Increased Mortality Persists after Treatment of Cushing’s Disease: A Matched Nationwide Cohort Study
por: Bengtsson, Daniel, et al.
Publicado: (2022)

Prednisolone is associated with a worse lipid profile than hydrocortisone in patients with adrenal insufficiency
por: Quinkler, Marcus, et al.
Publicado: (2016)

Reduced DNA methylation and psychopathology following endogenous hypercortisolism – a genome-wide study
por: Glad, Camilla A. M., et al.
Publicado: (2017)

Long-term Follow-up of 84 Patients With Giant Prolactinomas—A Swedish Nationwide Study
por: Himonakos, Christos, et al.
Publicado: (2023)

Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial
por: Chantzichristos, Dimitrios, et al.
Publicado: (2021)

Residual endogenous corticosteroid production in patients with adrenal insufficiency
por: Vulto, Annet, et al.
Publicado: (2019)

MON-431 Clinical Presentation of Metastases to the Pituitary: A Swedish Nationwide Study
por: Schill, Fredrika, et al.
Publicado: (2019)

Prevalence of Nelson’s syndrome after bilateral adrenalectomy in patients with cushing’s disease: a systematic review and meta-analysis
por: Papakokkinou, Eleni, et al.
Publicado: (2021)

The incidence of Cushing’s disease: a nationwide Swedish study
por: Ragnarsson, Oskar, et al.
Publicado: (2019)

SUN-450 Comorbidities in 419 Patients with Cushing's Disease in Remission: A Swedish Nationwide Study
por: Papakokkinou, Eleni, et al.
Publicado: (2019)

MON-159 High Mortality Rate in Oral Glucocorticoid Users: A Case-Control Study
por: Einarsdottir, Margret, et al.
Publicado: (2020)

Cardiovascular Risk Factors in Patients with Addison's Disease: A Comparative Study of South African and Swedish Patients
por: Ross, Ian Louis, et al.
Publicado: (2014)

High Mortality Rate in Oral Glucocorticoid Users: A Population-Based Matched Cohort Study
por: Einarsdottir, Margret J., et al.
Publicado: (2022)

MON-330 Cancer Incidence in 1,296 Patients with Acromegaly Is Not Increased: A Nationwide Population-Based Study
por: Esposito, Daniela, et al.
Publicado: (2020)

Non-functioning pituitary adenomas: indications for pituitary surgery and post-surgical management
por: Esposito, Daniela, et al.
Publicado: (2019)

SAT615 Long-term Effects Of Transsphenoidal Surgery On Headache In Patients With Pituitary Tumors - A Prospective Study
por: Hantelius, Victor, et al.
Publicado: (2023)

Illness perspectives in patients with primary aldosteronism
por: Ragnarsson, Oskar, et al.
Publicado: (2022)

Temporal relationship of sleep apnea and acromegaly: a nationwide study
por: Vouzouneraki, Konstantina, et al.
Publicado: (2018)

Patients with adrenal insufficiency have cardiovascular features associated with hypovolemia
por: Esposito, Daniela, et al.
Publicado: (2020)

Adrenal venous sampling in patients with ACTH-independent hypercortisolism
por: Papakokkinou, Eleni, et al.
Publicado: (2019)

Increasing Incidence of Primary Aldosteronism in Western Sweden During 3 Decades – Yet An Underdiagnosed Disorder
por: Gkaniatsa, Eleftheria, et al.
Publicado: (2021)

Response to Letter to the Editor From Singhania et al.: “Increasing Incidence of Primary Aldosteronism in Western Sweden During 3 Decades – Yet an Underdiagnosed Disorder”
por: Gkaniatsa, Eleftheria, et al.
Publicado: (2021)

Health Care Burden in Patients With Adrenal Insufficiency
por: Gunnarsson, Candace, et al.
Publicado: (2017)

Early Metabolic Benefits of Switching Hydrocortisone to Modified Release Hydrocortisone in Adult Adrenal Insufficiency
por: Bannon, Christopher A. M., et al.
Publicado: (2021)

Dose–exposure–IGF-I response of once-weekly somapacitan in adults with GH deficiency
por: Kildemoes, Rasmus Juul, et al.
Publicado: (2022)

The pre- and postoperative illness trajectory in patients with pituitary tumours
por: Jakobsson Ung, Eva, et al.
Publicado: (2019)

Current practice of glucocorticoid replacement therapy and patient-perceived health outcomes in adrenal insufficiency - a worldwide patient survey
por: Forss, M, et al.
Publicado: (2012)

Characterization of patients with adrenal insufficiency and frequent adrenal crises
por: Quinkler, Marcus, et al.
Publicado: (2021)

Editorial: Primary Adrenal Insufficiency - Quality of Life and Long-Term Outcome With Current Treatment Strategies
por: Esposito, Daniela, et al.
Publicado: (2022)

European Adrenal Insufficiency Registry (EU-AIR): a comparative observational study of glucocorticoid replacement therapy
por: Ekman, Bertil, et al.
Publicado: (2014)

Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5‐Lipoxygenase Activating Protein Inhibitor
por: Ericsson, Hans, et al.
Publicado: (2018)

Confounding effects of liquorice, hydrocortisone, and blood contamination on salivary cortisol but not cortisone
por: Imamovic, Marcus, et al.
Publicado: (2022)

Atypical or typical adrenocorticotropic hormone-producing pulmonary carcinoids and the usefulness of (11)C-5-hydroxytryptophan positron emission tomography: two case reports
por: Wahlberg, Jeanette, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_p5de7ttam740jm9mvh8tq9l9tg