Structural and electrophysiological dysfunctions due to increased endoplasmic reticulum stress in a long-term pacing model using human induced pluripotent stem cell-derived ventricular cardiomyocytes

BACKGROUND: Long-term ventricular pacing has deleterious effects and becomes more significant when cumulative percent ventricular pacing (Cum%VP) exceeds 40% of time. However, cellular disturbances and pathways by which pacing leads to myocardial disorders are not well understood. Attempts to resolv...

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Detalles Bibliográficos
Autores principales: Cui, Chang, Geng, Le, Shi, Jiaojiao, Zhu, Yue, Yang, Gang, Wang, Zidun, Wang, Jiaxian, Chen, Minglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426064/
https://www.ncbi.nlm.nih.gov/pubmed/28490375
http://dx.doi.org/10.1186/s13287-017-0566-6

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